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Clinical Trials Gov Annotation Guidelines v1

Author: Nic Dobbins (ndobb@uw.edu)

Welcome to the clinical-trials-gov annotation wiki! This is the central annotation guideline page, and is a work-in-progress. The purpose of this annotation is to produce gold-standard human-annotated training and test data for training machine learning models to derive clinical criteria from free-text documents. The corpus here is documents parsed from https://clinicaltrials.gov, limited to documents from 2018 and onwards.

Example:

Table of Contents

Home

Annotation Reference

Entities

• Demographics & Family
  • Age
  • Ethnicity
  • Family-Member
  • Language
  • Life-Stage-And-Gender
• Biomedical
  • Allergy
  • Birth
  • Condition
  • Death
  • Drug
  • Encounter
  • Immunization
  • Observation
  • Organism
  • Procedure
  • Provider
• Boolean, Negations, & Conjunctives
  • And
  • Assertion
  • Exception
  • Negation
  • Or
• Temporal & Numerical
  • Equality-Comparison
  • Temporal-Connection
• Other
  • Acuteness
  • Contraindication
  • Coreference
  • Criteria-Count
  • Indication
  • Location
  • Modifier
  • Other
  • Polarity
  • Risk
  • Severity
  • Stability
  • Study

Relations

• Abbrev-Of
• Caused-By
• Example-Of
• Equivalent-To
• Found-By
• If-Then
• Insurance
• Treatment-For
• Using

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What to do with...?

• Conditions or Procedures without specific names
• Past vs Present vs Future
• Symptoms
• Commas that mean Or
• Declarative statements
• Consent status
• Names