type of UU (unique-unique) is close to each other

[wbszhu]

Hi @anton，
I am using pairtools to parse the hichip data, choosing to keep only the type UU. But I find that it contains a certain number of pairs that are very close (<100bp). I wanna know whether this part should be marked as self-ligate.

UU pairs

A00545: 76:HW7 7KDSXY:1 :2345:17689:17065 chr1 2607 chr1 2616
A00543:178 : HVFNHDSXY:1 :1637 : 31684: 34100 chr1 4421 chr1 4476
A00543 :178 :HVFNHDSXY :1: 1649: 20039: 30843 chr1 28651 chr1 28718
A00543: 178 :HVF NHDSXY :1 : 1365: 30942:33692 chr1 30812 chr1 30820
A00545: 76:HW7 7KDSXY:1 :1673: 9001: 29794 chr1 40995 chr1 41030
A00543 :178 : HVFNHDSXY :1:1408:5647 :21574 chr1 41637 chr1 41645

luzhang.