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@neurogenomics

neurogenomics

Neurogenomics Lab, UK Dementia Research Institute at Imperial College London

🧠🧬 About Us 🧬🧠

Our research focuses on simple questions about complex brain traits: where do they occur (in which cell types)? When do they occur (at which developmental stages)? How do they occur (which quantitative traits of cells are affected)? We aim to develop the methods and datasets required to enable these questions to be answered systematically for any trait for which well-powered genetic data is available.

Popular repositories

  1. MAGMA_Celltyping MAGMA_Celltyping Public

    Find causal cell-types underlying complex trait genetics

    R 65 29

  2. MungeSumstats MungeSumstats Public

    Rapid standardisation and quality control of GWAS or QTL summary statistics

    R 64 14

  3. rworkflows rworkflows Public

    Continuous integration for R packages. 🔀 Automates testing ✅, documentation website building 📦, & containerised deployment 🐳.

    HTML 64 6

  4. orthogene orthogene Public

    🧬 o r t h o g e n e 🧬✨✨✨✨✨✨✨ Interspecies gene mapping✨✨✨✨✨ 🦠 🔁 🌱 🔁 🌳 🔁 🍎 🔁 🍊 🔁 🪱 🔁 🪰 🔁 🐟 🔁 🦎 🔁 🐓 🔁 🦇 🔁 🐄 🔁 🐖 🔁 🐐 🔁 🐎 🔁 🐈 🔁 🐕 🔁 🐁 🔁 🐒 🔁 🦧 🔁 🦍 🔁 🏃‍♀️

    R 35 4

  5. reanalysis_Mathys_2019 reanalysis_Mathys_2019 Public

    A re-analysis of the [Single-cell transcriptomic analysis of Alzheimer’s disease](https://www.nature.com/articles/s41586-019-1195-2) using a standardised data processing and pseudobulk differential…

    HTML 13 4

  6. EpiCompare EpiCompare Public

    Comparison, benchmarking & QC of epigenetic datasets

    HTML 12 3

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