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A model of a DNA supercoiling insulator in a transcription-translation system

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DNAsupercoil

A model of a DNA supercoiling insulator in a translation-transcription system.

A simulation of protein expression The concentration upstream gene is plotted and blue and the downstream gene in red.

References

  1. The base supercoiling model is adapted from:
    Yeung, Enoch, et al. "Modeling the effects of compositional context on promoter activity in an E. coli extract based transcription-translation system." Decision and Control (CDC), 2014 IEEE 53rd Annual Conference. IEEE, 2014.

  2. Elastic supercoiling model:
    Benham, Craig J. "Elastic model of supercoiling." Proceedings of the National Academy of Sciences 74.6 (1977): 2397-2401.

Disclaimer

This code was not been reviewed or tested sufficiently. There is no guarantee that it is correct.

This project is not active, it is just some old code.

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