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Identifying orthologs, paralogs and co-orthologs using BBH, phylogenetic tree analysis using ClustalW and conservation assessment using a simplified Valdar metric

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LucoDevro/Comparative-Genomics-of-Gloeobacter-and-Theobroma

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Comparative-Genomics-of-Gloeobacter-and-Theobroma

Code and limited results repository for the assignment for the course Comparative genomics, MSc of Bioinformatics, KU Leuven, 2023

Contents:

  • BLAST both organisms against each other (blast_both_all.pds)
  • Find BBHs for ortholog, paralog and co-ortholog detection (bbh.py)
  • BLAST a Gloeobacter proteins against 25 handpicked proteomes to find all homologs (get_homologs.pbs)
  • Parse results and identify homologs (homologs.py)
  • Create a simple NJ phylogenetic tree using ClustalW (homologs.phb)
  • Assess conservation across regions (conservation.py)

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Identifying orthologs, paralogs and co-orthologs using BBH, phylogenetic tree analysis using ClustalW and conservation assessment using a simplified Valdar metric

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