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Reproducibility repo for Shashikadze et al. "Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model".
The work focuses on assessing the host-pathogen 21 protein interaction affinity of the coronavirus family, having 44 different variants. In light of these 22 considerations, a GO-semantic scoring function is provided based on Gene Ontology (GO) graphs 23 for determining the binding affinity of any two proteins at the organism level.
Code for publication: Hypergraph Geometry Reflects Higher-Order Dynamics in Protein Interaction Networks; Kevin A. Murgas, Emil Saucan, Romeil Sandhu; Scientific Reports (2022)