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Sprint 8

Past due by 3 months 50% complete

Ancestry

  • Fixed imputation using Austin’s adversarial autoencoder or supervised PPCA solution, will be implemented in Ancestry
  • Works on hg19 (in addition to hg38 which already is supported), needs to be re-trained on hg19
  • Containerize ancestry module

PRS

  • PRS implemented and tested on large-enough (GIANT) data to verify that the model is viable from a ru…

Ancestry

  • Fixed imputation using Austin’s adversarial autoencoder or supervised PPCA solution, will be implemented in Ancestry
  • Works on hg19 (in addition to hg38 which already is supported), needs to be re-trained on hg19
  • Containerize ancestry module

PRS

  • PRS implemented and tested on large-enough (GIANT) data to verify that the model is viable from a runtime and statistical performance standpoint
  • Reach out to Paula about testing PRS with their data

Rare variant

  • Parent of origin effect testing

Proteomics

  • For upload prot data, link with normal annotation file from the start
  • For filtering, needs to be hooked up to webapp (Sprint 8/9)
  • Fetch a particular proteomics result: Create an API endpoint to stream a proteomic dataset. Write a Python library function, and create a CLI function to call that library function