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Single-Cell-Based Clinically-Related Mesoscale Pathology of Pancreatic Cancer

This repository contains all code used to produce the results and figures of the publication "Single-Cell-Based Clinically-Related Mesoscale Pathology of Pancreatic Cancer".

Visulization for figures:

  • figure1/figure1.R

    code for plots of heatmap, barplots and tSNE in figure1.

  • sup_figure1/sup_fig1.R

    code for boxplots in sfigure2.

  • figure2/figure2.R

    code for dotplot, tSNE, circluar barplot and chord plot in figure2.

  • figure3/figure3.R

    code for barplots and network graphs in figure3.

  • sup_figure3/sup_fig3.R

    code for barplots and network graphs in supplementary figures related to figure3.

  • figure4/figure4.R

    code for interaction heatmaps, os analysis and boxplots in figure4.

  • sup_figure4/sup_fig4.R

    code for correlation dotplots, density plots, boxplots and os analysis in supplementary figures related to figure4.

  • figure5/figure5.R

    code for dotplots, density plot, os analysis and boxplots in figure5.

  • image_plot.R for all images of single ROI showed in figures.

    usage example:

    image_plot.R -s p113_normal -t normal
    
  • cell_segmentation.cppipe for cell segmentation pipeline of CellProfiler

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