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Elementary Bioconductor interfaces to Pinello Lab SIMBA graph embeddings for single cell omics

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Simba4Bioc

Elementary Bioconductor interfaces to Pinello Lab SIMBA graph embeddings for single cell omics

This package provides R functions to build and interact with PyTorch biggraph artifacts generated using the simba python module.

The basic vignette (use 'Get Started' tab above) shows how to build interactive visualizations of joint embedding of cell and gene profiles like this one:

<iframe src="reference/figures/litpl.html" width="100%" height="360px"/>

Additional developments will target exploration of multimodal single cell assays.

(N.B. There are extraneous "Aa" symbols and mappings in the plot displayed above. This is a consequence of the introduction of extra symbols on the display. Improved plotly infrastructure or usage may help remove these meaningless tokens. Suggestions are welcome.)

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Elementary Bioconductor interfaces to Pinello Lab SIMBA graph embeddings for single cell omics

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