B cell slide updates

trvrb · Jul 15, 2022 · 91dc3df · 91dc3df
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diff --git a/bcells/images/2015-16_VE.png b/bcells/images/2015-16_VE.png
diff --git a/bcells/images/cid_titer_correlations.jpg b/bcells/images/cid_titer_correlations.jpg
diff --git a/bcells/images/nejmc2101667_f1.jpg b/bcells/images/nejmc2101667_f1.jpg
diff --git a/bcells/images/seropos_immunogenicity.jpg b/bcells/images/seropos_immunogenicity.jpg
diff --git a/bcells/images/tgsig.png b/bcells/images/tgsig.png
diff --git a/bcells/slides.html b/bcells/slides.html
@@ -122,26 +122,6 @@ <h3>Germinal centers</h3>
 					<h3>Affinity maturation</h3>
 					<img class="stretch" src="images/gc.png">
 				</section>
-
-				<section>
-					<h3>Dynamics in one GC</h3>
-					<img class="stretch" src="images/gc_dynamics.png">
-						<div class="citation">
-							<a href="http://cobeylab.uchicago.edu/publications">
-								Childs et al. 2015
-							</a>
-						</div>
-				</section>
-
-                <section>
-                    <h3>Ab feedback may diversify the repertoire</h3>
-                    <img class="stretch" src="images/em_div.png">
-                        <div class="citation">
-                            <a href="http://cobeylab.uchicago.edu/publications">
-                                Childs et al. 2015
-                            </a>
-                        </div>
-                        </section>
 
                 <section>
                     <h3>GC B cells evolve</h3>
@@ -485,13 +465,23 @@ <h3>Sin diminishes egg effects in 2012-2013?</h3>
                             </a>
                         </div>
                 </section>
+
+				<section>
+                    <h3>VE can suddenly drop in some age groups</h3>
+                    <img class="stretch" src="images/2015-16_VE.png" style="width: 50%; height: 50%;">
+					<div class="citation">
+                            <a href="https://academic.oup.com/jid/article/218/2/189/4816916">
+                                Flannery et al. 2018 (see also Skowronski et al. 2017)
+                            </a>
+                        </div>
+                </section>
 
                 <section>
                     <h3>Vaccine effectiveness tracks cohorts</h3>
                     <img src="images/cohort_ve.png" style="width: 60%; height: 60%;">
                         <div class="citation">
-                            <a href="https://www.medrxiv.org/content/10.1101/19001875v1">
-                                Arevalo et al. 2019
+                            <a href="https://elifesciences.org/articles/50060">
+                                Arevalo et al. 2020
                             </a>
                         </div>
                         </section>
@@ -506,6 +496,27 @@ <h3>Another curiosity: low VE in repeat vaccinees</h3>
                 </div>
                 </section>
 
+				<section>
+                    <h3>Prior infection influences vaccine responses</h3>
+                    <img class="stretch" src="images/seropos_immunogenicity.jpg" style="width: 90%; height: 90%;">
+                        <div class="citation">
+                            <a href="https://www.nejm.org/doi/full/10.1056/NEJMc2101667">
+                                Krammer et al. 2021
+                            </a>
+                </div>
+                </section>
+
+				<section>
+                    <h3>Innate immune signatures of vaccine responses</h3>
+                    <img class="stretch" src="images/tgsig.png" style="width: 90%; height: 90%;">
+                        <div class="citation">
+                            <a href="https://www.nature.com/articles/s41591-020-0769-8">
+                                Kotliarov et al. 2020
+                            </a>
+                </div>
+                </section>
+
+
 			</div>
 
 		</div>