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ClarkeErrorGrid

This has the function for the Clarke Error Grid

Made by Trevor Tsue 7/18/17

CLARKE ERROR GRID ANALYSIS ClarkeErrorGrid.py

Need Matplotlib Pyplot

The Clarke Error Grid shows the differences between a blood glucose predictive measurement and a reference measurement, and it shows the clinical significance of the differences between these values. The x-axis corresponds to the reference value and the y-axis corresponds to the prediction. The diagonal line shows the prediction value is the exact same as the reference value. This grid is split into five zones. Zone A is defined as clinical accuracy while zones C, D, and E are considered clinical error.

Zone A: Clinically Accurate This zone holds the values that differ from the reference values no more than 20 percent or the values in the hypoglycemic range (<70 mg/dl). According to the literature, values in zone A are considered clinically accurate. These values would lead to clinically correct treatment decisions.

Zone B: Clinically Acceptable This zone holds values that differe more than 20 percent but would lead to benign or no treatment based on assumptions.

Zone C: Overcorrecting This zone leads to overcorrecting acceptable BG levels.

Zone D: Failure to Detect This zone leads to failure to detect and treat errors in BG levels. The actual BG levels are outside of the acceptable levels while the predictions lie within the acceptable range

Zone E: Erroneous treatment This zone leads to erroneous treatment because prediction values are opposite to actual BG levels, and treatment would be opposite to what is recommended.

SYNTAX: plot, zone = ClarkeErrorGrid.clarke_error_grid(ref_values, pred_values)

INPUT: ref_values List of n reference values pred_values List of n prediciton values

OUTPUT: plot The Clarke Error Grid Plot returned by the function. Use this with plot.show() zone List of values in each zone. 0=A, 1=B, 2=C, 3=D, 4=E

EXAMPLE: from ClarkeErrorGrid import clarke_error_grid ... plot, zone = clarke_error_grid(ref_values, pred_values) plot.show()

References: [1] Clarke, WL. (2005). "The Original Clarke Error Grid Analysis (EGA)." Diabetes Technology and Therapeutics 7(5), pp. 776-779. [2] Maran, A. et al. (2002). "Continuous Subcutaneous Glucose Monitoring in Diabetic Patients" Diabetes Care, 25(2). [3] Kovatchev, B.P. et al. (2004). "Evaluating the Accuracy of Continuous Glucose- Monitoring Sensors" Diabetes Care, 27(8). [4] Guevara, E. and Gonzalez, F. J. (2008). Prediction of Glucose Concentration by Impedance Phase Measurements, in MEDICAL PHYSICS: Tenth Mexican Symposium on Medical Physics, Mexico City, Mexico, vol. 1032, pp. 259261. [5] Guevara, E. and Gonzalez, F. J. (2010). Joint optical-electrical technique for noninvasive glucose monitoring, REVISTA MEXICANA DE FISICA, vol. 56, no. 5, pp. 430434.

Made by: Trevor Tsue 7/18/17

Based on the Matlab Clarke Error Grid Analysis File Version 1.2 by: Edgar Guevara Codina codina@REMOVETHIScactus.iico.uaslp.mx March 29 2013

Copyright (c) 2008, Edgar Guevara Codina All rights reserved.

Redistribution and use in source and binary forms, with or without modification, are permitted provided that the following conditions are met:

  • Redistributions of source code must retain the above copyright notice, this list of conditions and the following disclaimer.
  • Redistributions in binary form must reproduce the above copyright notice, this list of conditions and the following disclaimer in the documentation and/or other materials provided with the distribution

THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

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