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slphyx/P.-falciparum-Dynamics

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A collection of the P. falciparum Dynamic models

A collection of the dynamic models of P. falciparum parasites in human before and during treatment with antimalarial drugs. These models were written in Wolfram language. The files in this repo can be opened by Mathematica(http://www.wolfram.com/mathematica) or CDF player(http://www.wolfram.com/cdf-player/).

  1. White, N.J., Chapman, D., & Watt, G.(1992) The effects of multiplication and synchronicity on the vascular distribution of parasites in falciparum malaria Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 590 - 597

  2. Anderson, R.M., May, R.M., & Gupta, S.(1989) Non - linear phenomena in host - parasite interactions Parasitology 99 Suppl, S59 - 79

  3. Kwiatkowski, D. & Nowak, M. (1991) Periodic and chaotic host-parasite interactions in human malaria Proceedings of the National Academy of Sciences of the United States of America 88, 5111-5113

  4. Simpson, J. A., et al. (2002). "Population dynamics of untreated Plasmodium falciparum malaria within the adult human host during the expansion phase of the infection." Parasitology 124(Pt 3): 247-263.

  5. Hoshen, M.B., Na - Bangchang, K., Stein, W.D., & Ginsburg, H.(2000) Mathematical modelling of the chemotherapy of Plasmodium falciparum malaria with artesunate : postulation of' dormancy', a partial cytostatic effect of the drug, and its implication for treatment regimens Parasitology 121 (Pt 3), 237 - 246

  6. Saralamba, S., et al. (2011). "Intrahost modeling of artemisinin resistance in Plasmodium falciparum." Proceedings of the National Academy of Sciences of the United States of America 108(1): 397-402.

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