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Purpose

This repository stores data used to test the mint methylation pipeline: https://github.com/sartorlab/mint.

Types of test data

Hybrid

Based on GSE52945, which is a hybrid of RRBS and hMe-Seal data. The test data were created by running full mint analysis on IDH2mut_1 and IDH2mut_2 versus NBM_1 and NBM_2 samples, and then backwards selecting the reads. Reads from the following region were selected to represent a variety of end results.

  • chr1:2209176-2214175 (hyper_mc_hyper_hmc)
  • chr2:71942840-72005839 (hypo_mc_hyper_hmc)
  • chr7:36074781-36102780 (hyper_hmc)
  • chr8:35090385-35095384 (hyper_mc)
  • chr11:67384075-67389174 (hypo_mc_hypo_hmc)
  • chr16:3046564-3096563 (hyper_mc_hyper_hmc and hyper_mc_hyper_hmc)
  • chr19:39702429-39752428 (hyper_mc_hypo_hmc)

Pulldown

This data is going to be based on IP methods measuring 5mC and 5hmC.

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