Research Interests

• Bioinformatics tool development
• Genetic logic circuit in living cells
• Laboratory automation

Publications

Selected articles

1. Mori H, Yachie N. A framework to efficiently describe and share reproducible DNA materials and construction protocols. Nat Commun. 2022 May 24;13(1):2894. doi: 10.1038/s41467-022-30588-x. PMID: 35610233; PMCID: PMC9130275.
2. Sakata RC^†, Ishiguro S^†, Mori H^†, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N. Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nat Biotechnol. 2020 Jul;38(7):865-869. doi: 10.1038/s41587-020-0509-0. Epub 2020 Jun 2. PMID: 32483365. ^†These authors equally contributed to this work.
3. Mori H, Evans-Yamamoto D, Ishiguro S, Tomita M, Yachie N. Fast and global detection of periodic sequence repeats in large genomic resources. Nucleic Acids Res. 2019 Jan 25;47(2):e8. doi: 10.1093/nar/gky890. PMID: 30304510; PMCID: PMC6344855.

Software tools

1. QUEEN
2. SPADE
3. patchworklib
4. pyCircos
5. sangerseq_viewer