nlmixr short course @ ACoP9 2018
The nlmixr team hosted a half-day hands-on workshop at ACoP9 2018 on simulation (RxODE) and parameter estimation using the free and open-source R-based nonlinear mixed effects modelling platform nlmixr. The course consisted of a mixture of lectures and hands-on exercises. Please find the agenda and a link to the course material below. Thank you to all participants from around the world who joined us for this exciting event!
| Time (Thursday 11 October) | Presenter | Topics |
|---|---|---|
| 8:00 | Matt Fidler | Introduction to nlmixr: an open-source package for pharmacometric modeling in R |
| nlmixr algorithms & functionality | ||
| Basic population PKPD modeling with nlmixr | ||
| - Model syntax | ||
| - Running nlmixr models | ||
| - Simulating from nlmixr models | ||
| - Comparison to NONMEM | ||
| 9:00 | Teun Post | Population model building made easy using an interactive shiny app: Introduction to shinyMixR |
| - nlmixr workflow | ||
| - shinyMixR | ||
| - xpose for nlmixr | ||
| 9:30 | Teun Post, Richard Hooijmaijers, Yuan Xiong, Rik Schoemaker, Justin Wilkins, Mirjam Trame | Introduction into Hands-On case studies |
| 9:30 | Hands-On: acop2018Tutorial | |
| 9:30 | Hands-On: Theophylline model | |
| 11:30 | Wenping Wang | Final Thoughts and Next Steps for nlmixr |
| 12:00 | END |
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Download and install nlmixr from here and use one of the different nlmixr installers depending on your operating system.
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Download the course material from the following links:
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[nlmixr Lecture] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/nlmixr-tutorial_final.pdf)
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[Hands-On Tutorial] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/acop2018Tutorial.zip)
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[Hands-On Theophylline model] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/Run1.R)
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[nlmixr Outlook] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/nlmixr%20outlook%20ACoP2018.pdf)
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[nlmixr CheatSheet] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/CheatSheet_nlmixr_10072018.pdf)
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[shinyMixR CheatSheet] (https://github.com/nlmixrdevelopment/ACoP9-2018/blob/master/CheatSheet_shinymixr_June%202018.pdf)
Best regards,
The nlmixr team
(Matthew Fidler, Teun M. Post, Richard Hooijmaijers, Rik Schoemaker, Mirjam N. Trame, Justin Wilkins, Yuan Xiong and Wenping Wang)