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Combinato Spike Sorting is a software for spike extraction, automatic spike sorting, manual improvement of sorting, artifact rejection, and visualization of continuous recordings and spikes. It offers a toolchain that transforms raw data into single/multi-unit spike trains. The software is largely modular, thus useful also if you are interested in just extraction or just sorting of spikes.
Combinato Spike Sorting works very well with large raw data files (tested with 100-channel, 15-hour recordings, i.e. > 300 GB of raw data). Most parts make use of multiprocessing and scale well with tens of CPUs.
Combinato is a collection of a few command-line tools and two GUIs, written in Python and depending on a few standard modules. It is being developed mostly for Linux, but it works on Windows and MacOS, too.
Since 2020, Combinato supports only Python3 and Qt5.