1.18.3

--noPlot produces NO PLOTS which makes it possible to use inside a Docker container

1.18.2

Release fixing an issue of a large gender imbalance for both somatic and germline analysis.

Still the copy-number will be imputed for large imbalance, but the issues start with a larger imbalance values.

1.18.1

Small bugfix for small panels and sex-biased control sets.

1.18.0

• new flag noPlot to save computational time
• new flag hg38
• the amount of females in the cohort for PAR region handling changed from 0.25 to 0.2

1.17.2

Some bug fixes (e.g. tumor-normal analysis works more stable)

Major changes:

• two new libraries (umap and dbscan) are required now for better clustering
• more variable regions remained now to separate clusters of samples better
• QC failed regions are shown not as a very small value, but can actually be somehow seen on IGV
• two issues closed

1.17.1

A very minor change from X11 plotting to Cairo. Useful when X11 is missing, but likely not affecting anything else.

1.17.0

Changes:

• tumor only calling: new module using germline functionality and modified germline output

1.16.6

Changes in germline mode:

• bugfix in IGV visualisation (QC-failed probes showed only once in seg files)

1.16.5

Germline:

• minor changes in output formatting (probes that are not used due to low quality are still shown in IGV as negative coverage probes)
• SuperRecall is gradually increasing if the sample is of low quality

1.16.4

Germline

• pseudoautosomal regions handling
• adaptive QC for the size of the panel
• overriding of genders

Somatic:

• added flags to regulate penalites for additional copy-numbers