Everything pertaining to methods for ECF reaction index scoring and visualization of clinical data during ECF vaccine trials.
The calculations here are derived from the following two papers:
- Rowlands, G.J.; Musoke, A.J.; Morzaria, Subhash P.; Nagda, S.M.; Ballingall, Keith T.; McKeever, Declan J. 2000. A statistically derived index for classifying East Coast fever reactions in cattle challenged with Theileria parva under experimental conditions. Parasitology 120: 371–381 CGSpace link
- Rowlands, G.J.; Musoke, A.J.; Nene, V.A., Bishop, R.P.; Nagda, S.M.; Morzaria, S.P. 2001. Application of principal component analysis for classifying East Coast fever reactions in cattle challenged with Theileria parva. Proceedings of the Society for Veterinary Epidemiology and Preventime Medicine, Noordwijkerhout, Netherlands, 2001: pp.57–66 CGSpace link
In addition to the above-mentioned two publications, we used unpublished (== ILRI internal) handover notes written by John Rowlands and Sonal Nagda on 09 November 2004, as well as their original design of an MS Access database for the calculation of ECF reaction indices.
You can try this on our Shiny app for ECF trial visualization.