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PAINTOR 2.1 Update
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gkichaev committed Jul 17, 2015
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# PAINTOR
Probabilistic Annotation INtegraTOR

## UPDATE 06/08/2015
#UPDATE 07/16/2015
Software (v2.1) has been updated with new strategy of setting Non-centrality Parameters (NCPs). See User Manual for details.

## *UPDATE 06/08/2015*
Announcing PAINTOR v2.0! We have expanded PAINTOR functionality to conduct fine-mapping with multi-ethnic cohorts. This latest release includes updates to the input formats and command line flags. Please see the new User Manual for complete details.

## Description

We provide a command line implementation of the PAINTOR and PAINTOR Trans-ethnic frameworks described in [Kichaev et al. (PLOS Genetics, 2014)](http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004722) and Kichaev and Pasaniuc (American Journal of Human Genetics, 2015)[http://www.cell.com/ajhg/abstract/S0002-9297(15)00243-8]. Briefly, PAINTOR is a statistical fine-mapping method that integrates functional genomic data with association strength from potentially multiple populations to prioritize variants for follow-up analysis. The software runs on multiple fine-mapping loci and/or populations simultaneously and takes as input the following data for each set of SNPs at a locus
We provide a command line implementation of the PAINTOR and PAINTOR Trans-ethnic frameworks described in [Kichaev et al. (PLOS Genetics, 2014)](http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004722) and [Kichaev and Pasaniuc (American Journal of Human Genetics, 2015)](http://www.cell.com/ajhg/abstract/S0002-9297(15)00243-8). Briefly, PAINTOR is a statistical fine-mapping method that integrates functional genomic data with association strength from potentially multiple populations to prioritize variants for follow-up analysis. The software runs on multiple fine-mapping loci and/or populations simultaneously and takes as input the following data for each set of SNPs at a locus


1. Summary Association Statistics (Z-scores)
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