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Updated vignette
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Jfortin1 committed Oct 17, 2022
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2 changes: 1 addition & 1 deletion DESCRIPTION
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Package: crisprBase
Version: 1.1.7
Version: 1.1.8
Date: 2022-09-27
Title: Base functions and classes for CRISPR gRNA design
Authors@R: person("Jean-Philippe", "Fortin", email = "fortin946@gmail.com", role = c("aut", "cre"))
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6 changes: 3 additions & 3 deletions README.Rmd
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# Overview

`crisprBase` provides S4 classes to represent nucleases, and more
specifically CRISPR nucleases. It also provides arithmetic
The `crisprBase` package is a core package of the [crisprVerse ecosystem](https://github.com/crisprVerse) that provides S4 classes for
representing CRISPR nucleases and base editors. It also provides arithmetic
functions to extract genomic ranges to help with the design and manipulation
of CRISPR guide-RNAs (gRNAs). The classes and functions are designed to work
with a broad spectrum of nucleases and applications, including
Expand All @@ -27,7 +27,7 @@ CRISPR nickases.

It provides a language and convention for our gRNA design ecosystem
described in our recent bioRxiv preprint:
["A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies"](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v2)
["The crisprVerse: a comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies"](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v3)


# Installation
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42 changes: 22 additions & 20 deletions README.md
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Expand Up @@ -51,19 +51,21 @@ Date: July 5, 2022

# Overview

`crisprBase` provides S4 classes to represent nucleases, and more
specifically CRISPR nucleases. It also provides arithmetic functions to
extract genomic ranges to help with the design and manipulation of
CRISPR guide-RNAs (gRNAs). The classes and functions are designed to
work with a broad spectrum of nucleases and applications, including
PAM-free CRISPR nucleases, RNA-targeting nucleases, and the more general
class of restriction enzymes. It also includes functionalities for
CRISPR nickases.
The `crisprBase` package is a core package of the [crisprVerse
ecosystem](https://github.com/crisprVerse) that provides S4 classes for
representing CRISPR nucleases and base editors. It also provides
arithmetic functions to extract genomic ranges to help with the design
and manipulation of CRISPR guide-RNAs (gRNAs). The classes and functions
are designed to work with a broad spectrum of nucleases and
applications, including PAM-free CRISPR nucleases, RNA-targeting
nucleases, and the more general class of restriction enzymes. It also
includes functionalities for CRISPR nickases.

It provides a language and convention for our gRNA design ecosystem
described in our recent bioRxiv preprint: [“A comprehensive Bioconductor
ecosystem for the design of CRISPR guide RNAs across nucleases and
technologies”](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v2)
described in our recent bioRxiv preprint: [“The crisprVerse: a
comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs
across nucleases and
technologies”](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v3)

# Installation

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## [1] stats graphics grDevices utils datasets methods base
##
## other attached packages:
## [1] crisprBase_1.1.5
## [1] crisprBase_1.1.6
##
## loaded via a namespace (and not attached):
## [1] rstudioapi_0.14 knitr_1.40 XVector_0.37.0
## [4] magrittr_2.0.3 GenomicRanges_1.49.1 BiocGenerics_0.43.1
## [7] zlibbioc_1.43.0 IRanges_2.31.2 rlang_1.0.4
## [1] rstudioapi_0.14 knitr_1.40 XVector_0.37.1
## [4] magrittr_2.0.3 GenomicRanges_1.49.1 BiocGenerics_0.43.4
## [7] zlibbioc_1.43.0 IRanges_2.31.2 rlang_1.0.5
## [10] fastmap_1.1.0 highr_0.9 stringr_1.4.1
## [13] GenomeInfoDb_1.33.5 tools_4.2.1 xfun_0.32
## [16] cli_3.3.0 htmltools_0.5.3 yaml_2.3.5
## [13] GenomeInfoDb_1.33.7 tools_4.2.1 xfun_0.32
## [16] cli_3.4.0 htmltools_0.5.3 yaml_2.3.5
## [19] digest_0.6.29 crayon_1.5.1 GenomeInfoDbData_1.2.8
## [22] S4Vectors_0.35.1 bitops_1.0-7 RCurl_1.98-1.8
## [25] evaluate_0.16 rmarkdown_2.15.2 stringi_1.7.8
## [28] compiler_4.2.1 Biostrings_2.65.2 stats4_4.2.1
## [22] S4Vectors_0.35.3 bitops_1.0-7 RCurl_1.98-1.8
## [25] evaluate_0.16 rmarkdown_2.16 stringi_1.7.8
## [28] compiler_4.2.1 Biostrings_2.65.3 stats4_4.2.1

# References

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6 changes: 3 additions & 3 deletions vignettes/crisprBase.Rmd
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Expand Up @@ -24,8 +24,8 @@ options("knitr.graphics.auto_pdf"=TRUE, eval=TRUE)

# Overview

`crisprBase` provides S4 classes to represent nucleases, and more
specifically CRISPR nucleases. It also provides arithmetic
The `crisprBase` package is a core package of the [crisprVerse ecosystem](https://github.com/crisprVerse) that provides S4 classes for
representing CRISPR nucleases and base editors. It also provides arithmetic
functions to extract genomic ranges to help with the design and manipulation
of CRISPR guide-RNAs (gRNAs). The classes and functions are designed to work
with a broad spectrum of nucleases and applications, including
Expand All @@ -35,7 +35,7 @@ CRISPR nickases.

It provides a language and convention for our gRNA design ecosystem
described in our recent bioRxiv preprint:
["A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies"](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v2)
["The crisprVerse: a comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies"](https://www.biorxiv.org/content/10.1101/2022.04.21.488824v3)


# Installation
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