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iMN22HE

Genome scale-metabolic model of Methanoperedens nitroreducens, a methanotrophic archaeon capable of anaerobic oxidation of methane.

This model is version-controlled under memote. A history report is publicly visible at https://computer-aided-biotech.github.io/iMN22HE.

Taxonomy Reference sequence Reactions Metabolites Genes
Candidatus Methanoperedens nitroreducens NZ_JMIY01000000 813 684 452

Model reconstruction

The draft iMN22HE was generated using KBase and ModelSEED from the genome sequence of Candidatus Methanoperedens nitroreducens (NZ_JMIY01000000). This was followed by manual curation based on the literature and biochemical information about ANME-2d and relative organisms. The reversibility of the reactions was generally determined from ΔG calculation.

The jupyter notebooks at ./notebooks are mainly about the annotation across different databases of the reactions, metabolites and genes in the model.

Generating memote reports

All memote commands have extensive help descriptions.

  1. For simple command line testing, check out memote run -h.
  2. To generate a pretty report of the current state of the model, check out memote report snapshot -h.

Cite this model

The model in the publication corresponds to the release v1.0 at github.

A link and the citation will be added here once available.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.