Genetic heterogeneity shapes brain connectivity in psychiatry

Authors: Clara A Moreau, Annabelle Harvey, Kumar Kuldeep,...

clara.moreau@umontreal.ca

Last authors: Bellec Pierre and Jacquemont Sebastien

Notebooks

Interactive brainmaps To navigate into the 29 CWAS results (beta values reported on brain maps for each FC-Profiles, before and after global signal adjustement) using nilearn

Generate Functional Connectivity profile (.md) This notebook requests stats.py and tools.py

Get CWAS Results (.md) This notebook needs stats.py and tools.py

Results

FC-profiles : 29 CWAS This folder contains all the beta values / p-values / q-values (n=2080 connections) for the 29 FC-profiles.

External repositories linked to this manuscript

Permutation Tests and cross-validations by A Harvey This repository contains all the scripts and notebooks for generating null models of betamaps (from this manuscript) through permutation and testing for significance.

Mind-GenesParallelCNV by JL Martineau to compute CNV calling parallel tasks in the most efficient method, in UKBiobank

Previous notebooks by C. Moreau and S. Urchs

Scripts

to preprocess resting-state_fMRI_data with NIAK (.m)

to_generate_connectomes with NIAK using MIST64 (.m)

to generate heatmaps for CellType and AHBA modules Fig 6 (.R)

to create chord diagrams Fig 5(.R)

MIST ATLAS

Multiscale dashboard