Model's codes for paper (Gene & Dev. 2014, v28, pg2120, Network dynamics determine the autocrine and paracrine signaling functions of TNF), which simulated TNF regulation in LPS, CpG and PIC treatement.
- Increase the stability by 3.5 fold.
- Open the chromatin for NFkB binding.
- MyD88 contributes more than TRIF in TNF mRNA processing (about 3 fold higher)