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Enhancing Boolean networks with continuous logical operators and edge tuning: smoothing simulations

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Enhancing Boolean networks with continuous logical operators and edge tuning

Copyright 2014-2019 Arnaud Poret

This work is licensed under the BSD 2-Clause License.

How to

  1. read my article
  2. clone smoosim:
    • run git clone https://github.com/arnaudporet/smoosim.git in a terminal emulator
    • or download it if you do not use Git
  3. read the file example.r

This work is implemented with R, tested with version 3.5.0 under Arch Linux.

Forthcoming

  • currently none

References

The example is a tiny sample of the epidermal growth factor receptor signaling pathway taken from [1].

  1. Melody K Morris, Julio Saez-Rodriguez, Peter K Sorger, Douglas A Lauffenburger (2010) Logic-based models for the analysis of cell signaling networks. Biochemistry, 49(15):3216-3224.