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When there's only one term ID in the dataframe passed as TERM2GENE in enricher #657

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mansi-aggarwal-2504 opened this issue Jan 11, 2024 · 0 comments

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@mansi-aggarwal-2504
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mansi-aggarwal-2504 commented Jan 11, 2024

Hello,
I was trying to reproduce the example for custom annotated gene list given here. I downloaded the data from the given url in the example.
I was able to get a similar result and I understand the GeneRatio and BgRatio.
Screenshot 2024-01-11 at 8 12 56 pm

But my case has a single term ID - I pass a TF's target genes in column 2, and column 1 is my annotation “TF”, which is the same for all rows. Input is a list of genes. I wanted to check if the overlap between these two lists is significant.

I try to reproduce it with the example in the documentation.

But I don't understand GeneRatio and BgRatio now, which is what I was getting in my case as well.
Screenshot 2024-01-12 at 1 10 13 pm

Could someone explain me the output when there's only one term ID in TERM2GENE input?

@mansi-aggarwal-2504 mansi-aggarwal-2504 changed the title When there's only one term ID passed to enricher's TERM2GENE When there's only one term ID passed as TERM2GENE in enricher Jan 11, 2024
@mansi-aggarwal-2504 mansi-aggarwal-2504 changed the title When there's only one term ID passed as TERM2GENE in enricher When there's only one term ID in the dataframe passed as TERM2GENE in enricher Jan 11, 2024
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