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PMID18775650: Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus
archetype needs checking
archetype question
checked
chemistry
Cyp51 target site
e.g. AE alteration in archetype
FRAST
new strain
unapproved until archetype AE checked
#212
opened Feb 1, 2024 by
jingluodatacurator
PMID:22906850 Effect of DMI-resistance mechanisms on cross-resistance patterns, fitness parameters and aflatoxin production in Aspergillus parasiticus Speare
archetype needs checking
checked
chemistry
Cyp51 target site
e.g. AE alteration in archetype
new strain
unapproved until archetype AE checked
#208
opened Dec 11, 2023 by
jingluodatacurator
PMID:21933337 Risk assessment studies on succinate dehydrogenase inhibitors, the new weapons in the battle to control Septoria leaf blotch in wheat
archetype needs checking
checked
chemistry
e.g. AE alteration in archetype
FRAST
Nearly ready for approval
needs UniProt id swap
new strain
SdhB/C/D target site
unapproved until archetype AE checked
Uniprot id query
#207
opened Nov 21, 2023 by
jingluodatacurator
PMID:30732567 Molecular characterization of carbendazim resistance of Fusarium species complex that causes sugarcane pokkah boeng disease
archetype needs checking
archetype question
beta tubulin target site
checked
chemistry
e.g. AE alteration in archetype
FRAST
new strain
unapproved until archetype AE checked
#194
opened Jul 21, 2023 by
MPiovesana
PMID:27415408 Homozygous and heterozygous point mutations in succinate dehydrogenase subunits b, c and d of Rhizoctonia cerealis conferring resistance to thifluzamide.
archetype needs checking
archetype question
checked
chemistry
diploid mode
e.g. AE alteration in archetype
FRAST
new strain
SdhB/C/D target site
unapproved until archetype AE checked
#188
opened Jul 19, 2023 by
MPiovesana
PMID:11036010 Genetic analysis of azole resistance in the Darlington strain of Candida albicans
archetype needs checking
checked
chemistry
Cyp51 target site
diploid mode
e.g. AE alteration in archetype
eg allele type 'transformant'
unapproved until archetype AE checked
#177
opened Jul 12, 2023 by
MPiovesana
PMID:18992352 Identification of three mutant loci conferring carboxin-resistance and development of a novel transformation system in Aspergillus oryzae
archetype needs checking
archetype question
checked
chemistry
e.g. AE alteration in archetype
eg allele type 'transformant'
Nearly ready for approval
needs strain to species mapping
new strain
next
question
SdhB/C/D target site
unapproved until archetype AE checked
Uniprot id query
#173
opened Jul 7, 2023 by
MPiovesana
PMID: 1423716 A single amino-acid change in the iron-sulphur protein subunit of succinate dehydrogenase confers resistance to carboxin in Ustilago maydis
archetype needs checking
archetype question
checked
chemistry
e.g. AE alteration in archetype
new strain
SdhB/C/D target site
unapproved until archetype AE checked
#165
opened Jul 4, 2023 by
MPiovesana
PMID: 12612806 Characterization of spontaneous mutants of Magnaporthe grisea expressing stable resistance to the Qo-inhibiting fungicide azoxystrobin
archetype needs checking
checked
chemistry
CytB target site
e.g. AE alteration in archetype
FRAST
Mo vs Mg species name
unapproved until archetype AE checked
Uniprot id query
#153
opened Jun 26, 2023 by
MPiovesana
PMID24119086: Site-directed mutagenesis of the P225, N230 and H272 residues of succinate dehydrogenase subunit B from Botrytis cinerea highlights different roles in enzyme activity and inhibitor binding
archetype needs checking
checked
chemistry
e.g. AE alteration in archetype
SdhB/C/D target site
unapproved until archetype AE checked
#149
opened Jun 22, 2023 by
jingluodatacurator
PMID: 27799210 Screening and Characterization of a Non-cyp51A Mutation in an Aspergillus fumigatus cox10 Strain Conferring Azole Resistance
archetype needs checking
checked
chemistry
Cyp51 target site
e.g. AE alteration in archetype
eg allele type 'transformant'
Nearly ready for approval
#143
opened Jun 15, 2023 by
MPiovesana
PMID:15215142 Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.
archetype needs checking
checked
chemistry
Cyp51 target site
e.g. AE alteration in archetype
unapproved until archetype AE checked
#140
opened Jun 14, 2023 by
CuzickA
PMID: 9871122 A single amino-acid substitution in the iron-sulphur protein subunit of succinate dehydrogenase determines resistance to carboxin in Mycosphaerella graminicola
archetype needs checking
checked
chemistry
eg allele type 'transformant'
SdhB/C/D target site
unapproved until archetype AE checked
#139
opened Jun 14, 2023 by
MPiovesana
PMID: 22536383 Mutagenesis and Functional Studies with Succinate Dehydrogenase Inhibitors in the Wheat Pathogen Mycosphaerella graminicola.
archetype needs checking
checked
chemistry
eg allele type 'transformant'
Nearly ready for approval
SdhB/C/D target site
unapproved until archetype AE checked
Uniprot id query
#138
opened Jun 12, 2023 by
MPiovesana
PMID: 17371828 A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations
archetype needs checking
checked
chemistry
Cyp51 target site
e.g. AE alteration in archetype
eg allele type 'transformant'
Nearly ready for approval
unapproved until archetype AE checked
#136
opened Jun 9, 2023 by
MPiovesana
Decide what do to when curators use different UniProt ids for the same gene in different publications
discuss
#125
opened May 24, 2023 by
CuzickA
PMID: 31860693 A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici
archetype needs checking
checked
chemistry
new strain
SdhB/C/D target site
unapproved until archetype AE checked
#124
opened May 24, 2023 by
CuzickA
List of potential publications containing host gene data for future curation
For Curation
Future
#113
opened Nov 30, 2022 by
CuzickA
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