Expression of KRAB-ZNF- transcription factors in The Cancer Genome Atlas study
KRAB-ZNF explorer is a web-based application for analyzing the expression of KRAB-ZNF transcription factors in the data from The Cancer Genome Atlas study.
Key functionalities cover:
- comparative analysis of KRAB-ZNF genes between normal and tumor samples,
- correlation of KRAB-ZNF expression with various clinico-pathological parameters,
- analysis and visualization of the link between patient survival and expression of KRAB-ZNF genes,
- analyses of the association between KRAB-ZNF expression and CpG methylation status,
- analyses of isoform expressions for KRAB-ZNF genes in normal and tumor samples,
- comparative analysis of KRAB-ZNF expression in normal tissues
KRAB-ZNF explorer is developed by Rafal Cylwa and collaborators: Urszula Oleksiewicz, Marta Gladych, Kornel Kielczewski and Przemyslaw Biecek. Analyses are performed based on The Cancer Genome Atlas (TCGA) data. R sources of the application are in this Github repository.