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KRAB-ZNF explorer - expression of KRAB-ZNF- transcription factors in The Cancer Genome Atlas study

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KRAB-ZNF explorer

Expression of KRAB-ZNF- transcription factors in The Cancer Genome Atlas study

KRAB-ZNF explorer is a web-based application for analyzing the expression of KRAB-ZNF transcription factors in the data from The Cancer Genome Atlas study.

Key functionalities cover:

  1. comparative analysis of KRAB-ZNF genes between normal and tumor samples,
  2. correlation of KRAB-ZNF expression with various clinico-pathological parameters,
  3. analysis and visualization of the link between patient survival and expression of KRAB-ZNF genes,
  4. analyses of the association between KRAB-ZNF expression and CpG methylation status,
  5. analyses of isoform expressions for KRAB-ZNF genes in normal and tumor samples,
  6. comparative analysis of KRAB-ZNF expression in normal tissues

KRAB-ZNF explorer is developed by Rafal Cylwa and collaborators: Urszula Oleksiewicz, Marta Gladych, Kornel Kielczewski and Przemyslaw Biecek. Analyses are performed based on The Cancer Genome Atlas (TCGA) data. R sources of the application are in this Github repository.

Screenshots: Survival curve Expression across cohorts Test results Heatmap

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