Cross-Trait Penalized Regression using Summary Statistics
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Updated
Nov 14, 2021 - R
Cross-Trait Penalized Regression using Summary Statistics
Julia implementation of Ge et al's PRScs
Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular manifestations in patients undergoing carotid endarterectomy
GAUDI: a penalized regression based PRS method designed specifically for admixed individuals
INVESTIGATING THE ASSOCIATION BETWEEN POLYGENIC RISK SCORE OF ADIPOSE TISSUE FUNCTION AND CARDIOVASCULAR DISEASE
Polygenic Risk Scores (PRS) pipeline.
Machine Learning in Genomics and Healthcare (COMP 565) Project
Machine Learning in Genomics and Healthcare (COMP 565) Project
This repository contains the programming codes used in Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types https://advances.sciencemag.org/content/7/3/eabd9036
Polygenic risk modeling with latent trait-related genetic components
power calculator for Genetic Risk Scores (GRS)
Those are the code files for producing the PheWAS analyses in the manuscript "Phenome-Wide Association Study of Polygenic Risk Score for Alzheimer’s Disease in Electronic Health Records". Part of our analyses included sensitive genomic data. Codes to produce AD PRS were not included here.
quincunx: an R package to query, download and wrangle PGS Catalog data
Utilities for working with PGS Catalog API and scoring files
Multi Kernel Linear Mixed Models for Complex Phenotype Prediction
Toolkit for the efficient construction and analysis of polygenic risk scores in R.
Toolkit to aid generation of advanced Polygenic Risk Scores (PRS) including SNP-allele tagging and interaction models, especially in HLA. Developed and maintained by Seth Sharp (S.sharp@exeter.ac.uk).
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