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mutation-topography

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AlexandrovLab / SigProfilerTopography

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SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA replication, and DNA transcription on the activities of different mutational processes. SigProfilerTopography elucidates the unique topographical characteristics of mutational signatures.

bioinformatics somatic-variants cancer-genomics mutation-analysis mutational-signatures mutation-topography
  • Updated May 18, 2024
  • Python

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