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Wording improvement in GWAS notebook
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tomwhite committed Jul 30, 2021
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"id": "plastic-running",
"metadata": {},
"source": [
"We passed a few arguments to the `vcf_to_zarr` conversion function, so it only loads the first alternate allele (`max_alt_alleles=1`), and to load extra VCF fields we are interested in (`GT`, `DP`, `GQ`, and `AD`). Also, `AD` needed defining as having a `Number` definition of `R` (one value for each allele, including the reference), since the dataset we are using defines it as `.` which means \"unknown\".\n",
"We passed a few arguments to the `vcf_to_zarr` conversion function, so it only converts the first alternate allele (`max_alt_alleles=1`), and to load extra VCF fields we are interested in (`GT`, `DP`, `GQ`, and `AD`). Also, `AD` needed defining as having a `Number` definition of `R` (one value for each allele, including the reference), since the dataset we are using defines it as `.` which means \"unknown\".\n",
"\n",
"Now the data has been written as Zarr, all downstream operations on will be much faster. Note that sgkit uses an [Xarray](http://xarray.pydata.org/en/stable/) dataset to represent the VCF data, where Hail uses MatrixTable."
]
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