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The mouse resource are missing important interactions that should be possible to convert #76

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johan-gson opened this issue Nov 29, 2023 · 2 comments
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@johan-gson
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Describe the bug
Hi and thanks for a nice tool. For example, Cxcl9 is missing as ligand in the database, while Cxcl10 is there, and they have many receptors in common. Converting CXCL9 to Cxcl9 should be doable? I'm guessing something has gone wrong and that many interactions are missing in the mouse data.

To Reproduce
Just look in the database

@johan-gson johan-gson added bug Something isn't working help wanted Extra attention is needed labels Nov 29, 2023
@dbdimitrov
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Hi @johan-gson,

Indeed, there are some interactions missing in the mouse data, very likely as their orthologues were missing from the mapping reference (homologene), that we used.

I plan to rebuilt the Consensus and MouseConsensus resources soon using orthologues from UniProt, and also provide a short tutorial for resource conversion.

I will keep you updated.

@johan-gson
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Thank you!

Best,

Johan

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