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Adding LRT test #176

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wxicu opened this issue Oct 4, 2023 · 3 comments · May be fixed by #178
Open

Adding LRT test #176

wxicu opened this issue Oct 4, 2023 · 3 comments · May be fixed by #178

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@wxicu
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wxicu commented Oct 4, 2023

Hey, thanks for developing pydeseq2!
I used to perform DGE analysis with edgeR and happy now to see there is a python package. I am comparing the result of pydeseq2 and edger on the same dataset and I see there is a large difference. Is it possible to add likelihood ratio test like in deseq2 with dds = DESeq(dds, test="LRT") in the future? Thanks a lot!

@BorisMuzellec
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Hi @wxicu, thanks for the suggestion! It's in our TODO list :) we hope to open a PR in the next few weeks

@bengroves
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Hi, thanks for all your work with PyDESeq2. Any idea when the LRT changes are going to be pushed to production?

@BorisMuzellec
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Hi @bengroves, unfortunately the LRT PR (#178) isn't currently being developed, but we'd be happy to help anyone who'd like to revive it or create a new one

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