Homeocurvature adaptation of phospholipids to pressure in deep-sea invertebrates

Jacob R. Winnikoff, Daniel Milshteyn, Sasiri J. Vargas-Urbano, Miguel A. Pedraza, Aaron M. Armando, Oswald Quehenberger, Alexander Sodt, Richard E. Gillilan, Edward A. Dennis, Edward Lyman, Steven H. D. Haddock, and Itay Budin

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Guide to manuscript repo

0. homeocurvature-2024.Rproj - Run any of the included R code from within this project to have the relative paths set up by here() work correctly.

1. 01-rawdata - Mostly SAXS profiles and lipidomics data in ASCII and spreadsheet formats. Some other input files for R scripts are included here.

2. 02-saxsanalysis - Scripts for and results from parametric fitting of lamellar and inverted SAXS profiles. Data and Shiny code for the ctenophore SAXS P-T eXplorer are also present here.

3. 02-tidydata - Intermediate "tidied" lipidomics data files.

4. 03-scripts - R scripts to run all statistical analyses and visualize results. lamellar_mcg subdirectory contains a JScatter python implementation of the Modified Caillé Gaussian (MCG) model for multilamellar vesicle SAXS.

5. 04-mainfigs - PDF and PNG versions of all main-text figures.

6. 04-suppfigs - PDF and PNG versions of all SI figures.