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Differential splicing analysis using rMATS #115

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dshechter opened this issue Apr 21, 2023 · 1 comment
Open

Differential splicing analysis using rMATS #115

dshechter opened this issue Apr 21, 2023 · 1 comment
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enhancement New feature or request

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@dshechter
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Description of feature

Differential splicing is a frequent consequence observed in RNA-Seq data. rMATS (https://rnaseq-mats.sourceforge.net/) is the most frequently used analysis tool, providing outputs for skipped exons, alternative 5' and 3' splice sites, mutually exclusive exons, and retained introns. Performing this analysis (and maybe some overview plots, like violin plots of the delta "percent spliced in" deltaPSI metric) would be an important new feature.
Thanks for working on this great new pipeline.

@dshechter dshechter added the enhancement New feature or request label Apr 21, 2023
@pinin4fjords
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Thanks @dshechter - as with all feature requestors I encourage you to make a PR to the modules repository to add the tool. There are development instructions here https://nf-co.re/developers/tutorials/dsl2_modules_tutorial.

With a tool module in place we can then help you integrate it into this workflow.

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