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Novel ultrafast suite for high-throughput & high-content multiparameter screening as in drug discovery. It has unique modules for QC, bias correction, similarity measurement, clustering and visualization. It can process hundreds of samples with many markers in a few hours not days & circumvents bath effect. It couples with any plate reader.

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morchalabi/COMPARE-suite

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COMPARE-suite

COMPARE-suite is a novel ultra-fast software suite (pipeline) to analyze small to large scale multiparameter (marker) screenings extensively used in drug discovery and personalized medicine. It

  1. consists of several unique modules for experiment quality control, bias correction, similarity measurement, clustering and visualization
  2. can process the output of any screening technology like mass cytometer, flow cytometer and high-content microscope in both text and binary data format
  3. is data-size independent
  4. can effectively circumvent background noise and signal shift (signal drift and batch effect)
  5. does not need dimension reduction
  6. does not need subsampling
  7. is equipped with multithreading mechanism for parallel computing, processing hundreds of samples with numerous markers containing millions of events in a few hours rather than days
  8. can also run through graphical user interface on desktop machines or command-line interface on computer servers

For more information check out its Wiki.

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Novel ultrafast suite for high-throughput & high-content multiparameter screening as in drug discovery. It has unique modules for QC, bias correction, similarity measurement, clustering and visualization. It can process hundreds of samples with many markers in a few hours not days & circumvents bath effect. It couples with any plate reader.

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