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Python and R programs used in the identification of repurposed drugs against viruses responsible for causing epidemics/pandemics

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manojk-imtech/viralrep

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DrugRepV

DrugRepV folder contains the programs (Python and R) used in identification of repurposed drugs for viruses

  • drugbank_extract.ipynb - Python program used to extract the repurposed drug from experimenatlly validated antivirals (high and low frequency). Further, to check the common repurposed drugs between the resulted positive (high efficacy) and negative (low efficacy) identified drugs.

  • drugrepv_repurposed_drugs.ipynb - The python pipeline to identify the repurposed drugs against epidemic/pandemic viruses.

  • drugrepV_heatmap.ipynb - Python program to genrate the heatmap with identified repurposed drugs with their confofence score (s).

  • alluvial_plot.R - R script to generate highly user-friendly alluvial plot.

  • pathway_analysis.R - R Script to generate a heatmap of the top KEGG pathways involved in viral infection

  • data.zip - Input data of 14 epidemic/pandemic viruses used in analysis.

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Python and R programs used in the identification of repurposed drugs against viruses responsible for causing epidemics/pandemics

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