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Papers & such!

Coming soon!

  • Lipid metabolism in Mycobacterium tuberculosis-infected macrophages
  • Modeling the START transition in the budding yeast cell cycle

#Co-primary authors. *Co-corresponding authors. In bold: Members of JRaviLab.

2021 Reconciling Multiple Connectivity Scores for Drug Repurposing

Kewalin Samart#, Phoebe Tuyishime#, Arjun Krishnan, **Janani Ravi**. Reconciling Multiple Connectivity Scores for Drug Repurposing. Briefings in Bioinformatics. 2021

2021 A Broadly Conserved Deoxycytidine Deaminase Protects Bacteria from Phage Infection

Geoffrey B Severin#, Brian Y Hsueh#, Clinton A Elg, John A Dover, Christopher R Rhoades, Alex J Wessel, Benjamin J Ridenhour, Eva M Top, Janani Ravi, Kristin D Parent, Chris M Waters. A Broadly Conserved Deoxycytidine Deaminase Protects Bacteria from Phage Infection. bioRxiv. 2021.

2021 S-layers in Gram-Positive Pathogens

Janani Ravi#, Fioravanti A#. S-layers: the proteinaceous multifunctional armours of Gram-positive pathogens. Frontiers in Microbiology. 2021

2021 New Brazilian M. tuberculosis lineage

Syeda Anum Hadi#, Ida V Kolte#, Evan P Brenner#, Jennifer Gardy, EAT Cunha, L Ferrazoli, DA Villela, RS Santos, Janani Ravi, Srinand Sreevatsan, Paulo C Basta. Identification of a predominant genotype of Mycobacterium tuberculosis in Brazilian indigenous population. Scientific Reports. 2021 Jan 13;11(1):1224. PMID: 33441660

2020 Psp evolution across the tree of life

Janani Ravi*, Vivek Anantharaman, Samuel Chen, Pratik Datta, L Aravind, Maria L Gennaro. Phage-shock-protein (Psp) Envelope Stress Response: Evolutionary History & Discovery of Novel Players. bioRxiv. 2020

2019 Tcy Cystine transporters in Staphylococcus aureus

Joshua M Lensmire, Jack P Dodson, Brian Y Hsueh, Michael R Wischer, Phillip C Delekta, John C Shook, Elizabeth N Ottosen, Paige J Kies, Janani Ravi, Neal D Hammer. The Staphylococcus aureus Cystine Transporters TcyABC and TcyP Facilitate Nutrient Sulfur Acquisition during Infection. Infect Immun. 2020 Feb 20;88(3). doi: 10.1128/IAI.00690-19. Print 2020 Feb 20. PMID: 31843961.

2018 Psp systems in Actinobacteria

Janani Ravi, Vivek Anantharaman, L Aravind, Maria L Gennaro. Variations on a theme: evolution of the phage-shock-protein system in Actinobacteria. Antonie Van Leeuwenhoek. 2018 May;111(5):753-760. doi: 10.1007/s10482-018-1053-5. Epub 2018 Feb 27. PubMed PMID: 29488183.

2017 Psp systems in Gram-positive bacteria

contributed to all the figures and computational analyses in this review.
Manganelli R, Gennaro ML. Protecting from Envelope Stress: Variations on the Phage-Shock-Protein Theme. Trends Microbiol. 2017 Mar;25(3):205-216. doi: 10.1016/j.tim.2016.10.001. Epub 2016 Nov 16. PMID: 27865622.

2016 Sigma-factor network in Mtb

Rinki Chauhan, Janani Ravi, Pratik Datta, Tian Chen, Dirk Schnappinger, Kevin E Bassler, Gabor Balázsi, Maria L Gennaro. Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis. Nat Commun. 2016 Mar 31;7:11062. doi: 10.1038/ncomms11062. PMID: 27029515.

2015 Psp in Mtb

Pratik Datta, Janani Ravi, Valentina Guerrini, Rinki Chauhan, Matt B Neiditch, Scarlet S Shell, Sarah M Fortune, Baris Hancioglu, Oleg A Igoshin, Maria L Gennaro. The Psp system of Mycobacterium tuberculosis integrates envelope stress-sensing and envelope-preserving functions. Mol Microbiol. 2015 Aug;97(3):408-22. doi: 10.1111/mmi.13037. Epub 2015 May 26. PMID: 25899163.

2014 VitD in Mtb-infected macrophages

Hugh Salamon, Natalie Bruiners, Karim Lakehal, Lanbo Shi, Janani Ravi, Ken D Yamaguchi, Richard Pine, Maria L Gennaro. Cutting edge: Vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection. J Immunol. 2014 Jul 1;193(1):30-34. doi: 10.4049/jimmunol.1400736. Epub 2014 Jun 4. PMID: 24899504.

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