FDAopenR : R package for accessing and manipulating openFDA API.
The following functions are implemented:
- ndcToString: Converting numeric ndc values to appropriate ndc string values for open FDA API search
- listSF: Listing Search Field Parameters
- extractFDA: Extracts relevant information from the open FDA API
# you'll want to see the vignettes, trust me
library("devtools")
devtools::install_github("ck2136/FDAopenR")
# for now not on CRAN :(library("FDAopenR")
library("dplyr")
##
## Attaching package: 'dplyr'
## The following objects are masked from 'package:stats':
##
## filter, lag
## The following objects are masked from 'package:base':
##
## intersect, setdiff, setequal, union
# current verison
packageVersion("FDAopenR")
## [1] '0.2.0.9000'
# - - - - - - - - - - - - - - - - - - - - - #
# Instantiate example classes
# - - - - - - - - - - - - - - - - - - - - - #
drug1 <- new(Class="Drug",
ndc = 687889736,
apikey="Y3CgaZj67AotB7b4XLhzHJTY7oBWKUC3u1fYulw8"
)
## *** FDA Class Inspection ***
## *** FDA Class Inspection Complete: APIKEYFOUND***
device1 <- new(Class="Device",
apikey="Y3CgaZj67AotB7b4XLhzHJTY7oBWKUC3u1fYulw8"
)
## *** FDA Class Inspection ***
## *** FDA Class Inspection Complete: APIKEYFOUND***
food1 <- new(Class="Food",
apikey="Y3CgaZj67AotB7b4XLhzHJTY7oBWKUC3u1fYulw8"
)
## *** FDA Class Inspection ***
## *** FDA Class Inspection Complete: APIKEYFOUND***
other1 <- new(Class="Other",
ndc=6382447364,
apikey="Y3CgaZj67AotB7b4XLhzHJTY7oBWKUC3u1fYulw8"
)
## *** FDA Class Inspection ***
## *** FDA Class Inspection Complete: APIKEYFOUND***drug1@ndcquery
## character(0)
drug1 <- ndcToString(drug1)
drug1@ndcquery
## [1] "68788-9736"
#ndcToString(device1) # this will be an error!
other1 <- ndcToString(other1)
other1 %>% str(max.level=2)
## Formal class 'Other' [package "FDAopenR"] with 13 slots
## ..@ nsdeTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slots
## ..@ ndc : num 6.38e+09
## ..@ ndcquery : chr "63824-4736-4"
## ..@ url : chr "https://api.fda.gov/"
## ..@ apikey : chr "Y3CgaZj67AotB7b4XLhzHJTY7oBWKUC3u1fYulw8"
## ..@ endpointfront: chr "other"
## ..@ endpointback : chr "nsde"
## ..@ searchfield : chr(0)
## ..@ aeTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slots
## ..@ prodTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slots
## ..@ ndcTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slots
## ..@ reTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slots
## ..@ dafTab :'data.frame': 0 obs. of 0 variables
## Formal class 'data.frame' [package "methods"] with 4 slotslistSF(drug1,"event") %>% head
## [1] "authoritynumb" "companynumb" "duplicate" "fulfillexpeditecriteria"
## [5] "occurcountry" "patient"
listSF(drug1,"label") %>% head
## [1] "abuse" "abuse_table" "accessories" "accessories_table"
## [5] "active_ingredient" "active_ingredient_table"
listSF(drug1,"ndc") %>% head
## [1] "product_id" "product_ndc" "spl_id" "product_type" "finished" "brand_name"
listSF(device1,"510k") %>% head
## [1] "address_1" "address_2" "advisory_committee"
## [4] "advisory_committee_description" "applicant" "city"
listSF(device1,"classification") %>% head
## [1] "definition" "device_class" "device_name" "gmp_exempt_flag"
## [5] "implant_flag" "life_sustain_support_flag"
listSF(device1,"enforcement") %>% head
## [1] "address_1" "address_2" "center_classification_date" "city"
## [5] "classification" "code_info"
listSF(device1,"event") %>% head
## [1] "adverse_event_flag" "date_facility_aware" "date_manufacturer_received" "date_of_event"
## [5] "date_received" "date_report"
listSF(device1,"pma") %>% head
## [1] "advisory_committee" "advisory_committee_description" "ao_statement"
## [4] "applicant" "city" "date_received"
listSF(device1,"recall") %>% head
## [1] "event_date_initiated" "event_date_created" "event_date_posted" "event_date_terminated"
## [5] "recall_status" "recalling_firm"
listSF(device1,"registrationlisting") %>% head
## [1] "establishment_type" "k_number" "pma_number" "products" "proprietary_name"
## [6] "registration"
listSF(device1,"udi") %>% head
## [1] "brand_name" "catalog_number" "commercial_distribution_end_date"
## [4] "commercial_distribution_status" "company_name" "customer_contacts"
listSF(food1,"enforcement") %>% head
## [1] "address_1" "address_2" "center_classification_date" "city"
## [5] "classification" "code_info"
listSF(food1,"event") %>% head
## [1] "consumer" "date_created" "date_started" "outcomes" "products" "reactions"
listSF(other1) %>% head
## [1] "package_ndc" "package_ndc11" "proprietary_name"
## [4] "dosage_form" "marketing_category" "application_number_or_citation"extractFDA(drug1,"event","receivedate:[20040101+TO+20081231]&limit=15")[1:5,1:5]
## receiptdateformat receiver seriousnessdeath companynumb receivedateformat
## 1 102 NA 1 JACAN16471 102
## 2 102 NA 1 WAES 97101426 102
## 3 102 NA <NA> CDN/97/00530/LEX 102
## 4 102 NA <NA> USA/97/02459/LAS 102
## 5 102 NA <NA> 1997002193-FJ 102
extractFDA(drug1,"ndc", "finished:true&limit=3")[1:5,1:5]
## product_ndc marketing_end_date generic_name labeler_name
## 1 0409-6139 20220801 water Hospira, Inc.
## 2 71919-080 <NA> ARISTOLOCHIA CYMBIFERA FLOWER Washington Homeopathic Products
## 3 74028-355 <NA> Isopropyl Alcohol Creative Consumer Products, Inc.
## NA <NA> <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA> <NA>
## brand_name
## 1 Sterile Water
## 2 Aristolochia milhomens
## 3 Dionis Hand Sanitizer
## NA <NA>
## NA.1 <NA>
extractFDA(device1,"registrationlisting",'')[1:5,1:5]
## proprietary_name
## 1 Sit-up bed supporter ladder
## NA NULL
## NA.1 NULL
## NA.2 NULL
## NA.3 NULL
## establishment_type
## 1 Manufacture Medical Device, Manufacture Medical Device for Another Party (Contract Manufacturer), Export Device to the United States But Perform No Other Operation on Device
## NA NULL
## NA.1 NULL
## NA.2 NULL
## NA.3 NULL
## registration.registration_number registration.fei_number registration.status_code
## 1 3012946064 3012946064 1
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.initial_importer_flag registration.reg_expiry_date_year registration.name
## 1 N 2021 NINGBO GIBBON SPORTS CULTURE CO., LTD.
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.address_line_1 registration.address_line_2 registration.city registration.state_code
## 1 1001,1#, SHANGDONG BUSINESS CENTRE, YINZHOU Ningbo Zhejiang
## NA <NA> <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA> <NA>
## registration.iso_country_code registration.zip_code registration.postal_code registration.us_agent.name
## 1 CN 315040 Fanny Zhao
## NA <NA> <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA> <NA>
## registration.us_agent.business_name registration.us_agent.bus_phone_area_code registration.us_agent.bus_phone_num
## 1 J & F Technology Service 909 5100201
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.us_agent.bus_phone_extn registration.us_agent.fax_area_code registration.us_agent.fax_num
## 1
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.us_agent.email_address registration.us_agent.address_line_1 registration.us_agent.address_line_2
## 1 info@jf-yiliao.com 19838 Moon Shadow Circle
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.us_agent.city registration.us_agent.state_code registration.us_agent.iso_country_code
## 1 Walnut CA US
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.us_agent.zip_code registration.us_agent.postal_code registration.owner_operator.firm_name
## 1 91789 NINGBO GIBBON SPORTS CULTURE CO., LTD.
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
## registration.owner_operator.owner_operator_number registration.owner_operator.official_correspondent.first_name
## 1 10053544 Xudong
## NA <NA> <NA>
## NA.1 <NA> <NA>
## NA.2 <NA> <NA>
## NA.3 <NA> <NA>
## registration.owner_operator.official_correspondent.middle_initial
## 1
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.official_correspondent.last_name
## 1 Feng
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.official_correspondent.subaccount_company_name
## 1
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.official_correspondent.phone_number
## 1 86-574-83031127-x
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.contact_address.address_1 registration.owner_operator.contact_address.address_2
## 1 1001,1#, SHANGDONG BUSINESS CENTRE, YINZHOU
## NA <NA> <NA>
## NA.1 <NA> <NA>
## NA.2 <NA> <NA>
## NA.3 <NA> <NA>
## registration.owner_operator.contact_address.city registration.owner_operator.contact_address.state_code
## 1 Ningbo CN-ZJ
## NA <NA> <NA>
## NA.1 <NA> <NA>
## NA.2 <NA> <NA>
## NA.3 <NA> <NA>
## registration.owner_operator.contact_address.state_province
## 1 Zhejiang
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.contact_address.iso_country_code
## 1 CN
## NA <NA>
## NA.1 <NA>
## NA.2 <NA>
## NA.3 <NA>
## registration.owner_operator.contact_address.postal_code pma_number k_number
## 1 315040
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA>
extractFDA(device1,"udi",'public_version_status:Update')[1:5,1:5]
## has_donation_id_number mri_safety record_status is_labeled_as_nrl is_rx
## 1 false Labeling does not contain MRI Safety Information Published false true
## NA <NA> <NA> <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA> <NA> <NA>
## NA.2 <NA> <NA> <NA> <NA> <NA>
## NA.3 <NA> <NA> <NA> <NA> <NA>
extractFDA(device1,"pma",'decision_code:APPR&limit=3')[1:5,1:5]
## pma_number supplement_number applicant street_1 street_2
## 1 P090016 S018 MERZ NORTH AMERICA, INC 4133 COURTNEY ROAD SUITE 10
## 2 P810017 S001 ADVANCED MEDICAL OPTICS, INC. 2525 DUPONT DR.
## 3 P010030 S141 ZOLL MANUFACTURING CORPORATION 121 GAMMA DR
## NA <NA> <NA> <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA> <NA> <NA>
extractFDA(food1, "enforcement", 'report_date:[20040101+TO+20131231]&limit=3')[1:5,1:5]
## country city address_1
## 1 United States Medford 2500 S Pacific Hwy
## 2 United States Newark 170 Avenue L
## 3 United States Boston 18 Bunker Hill Industrial Park
## NA <NA> <NA> <NA>
## NA.1 <NA> <NA> <NA>
## reason_for_recall address_2
## 1 Product received from supplier is being recalled due to the potential to be contaminated with Salmonella
## 2 Products have the potential to be contaminated with Listeria monocytogenes.
## 3 Products contain recalled Gill's Onions due to Listeria monocytogenes
## NA <NA> <NA>
## NA.1 <NA> <NA>
extractFDA(food1, "event", 'date_created:[20040101+TO+20131231]&limit=5')[1:5,1:5]
## report_number outcomes date_created
## 1 115666 Patient Visited Healthcare Provider 20090715
## 2 100210 Patient Visited Healthcare Provider 20080207
## 3 112318 Other Outcome 20090423
## 4 130489 Other Outcome 20101001
## 5 136173 Medically Important 20110301
## reactions
## 1 SWELLING, PHARYNGITIS
## 2 WEIGHT DECREASED, TREMOR, SKIN DISCOLOURATION, PRURITUS, PARAESTHESIA, LOCALISED OEDEMA, EYE IRRITATION, DIARRHOEA, CONVULSION, BURNING SENSATION, ASTHENIA, ALOPECIA
## 3 VOMITING, NAUSEA, MALAISE, HAEMATOCHEZIA, DIARRHOEA, CHILLS, ABDOMINAL PAIN
## 4 VOMITING, THROAT IRRITATION, SNEEZING, NASOPHARYNGITIS, LETHARGY, FEELING OF BODY TEMPERATURE CHANGE, BODY TEMPERATURE INCREASED
## 5 SARCOMA, HEADACHE, FEELING ABNORMAL
## date_started
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 NA
extractFDA(other1, query='marketing_start_date:[20040101+TO+20131231]&limit=5')[1:5,1:5]
## proprietary_name application_number_or_citation product_type
## 1 Isopropyl Rubbing Alcohol With Wintergreen part333A HUMAN OTC DRUG
## 2 Purell Advanced Refreshing Aloe part333E HUMAN OTC DRUG
## 3 Korres Wild Rose Mineral Foundation Wrmf2 Light Spf 30 part352 HUMAN OTC DRUG
## 4 Jet Lag <NA> HUMAN OTC DRUG
## 5 Prednisone ANDA085161 HUMAN PRESCRIPTION DRUG
## marketing_start_date package_ndc
## 1 20120722 52862-009-12
## 2 20120314 21749-705-89
## 3 20110202 10279-120-10
## 4 20110301 55714-1110-0
## 5 20131120 52125-775-08