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Analysis pipeline for modeling of illness perception one year after COVID-19

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CovILD-IPQ

Analysis pipeline for modeling of illness perception one year after COVID-19

Summary

We investigate severity and quality of illness perception (IP) in a cross-sectional observational cohort of COVID-19 convalescents (CovILD study) suffering from persistent somatic symptoms or heart/lung abnormalities at one year after diagnosis. By regularized regression and unspervised clustering we could discover a strong association of persistent somatic symptoms (PSS) such as fatigue, physical performance loss or sleep problems with the total IP severity and its emotion/concern/consequences component. For details, please refer to our paper.


Factors influencing overall illness perception (IP, A) and its emotion/concern/consequences component (B) in COVID-19 convalescents at one year after SARS-CoV-2 infection. The key influencing factors were explanatory variables selected concomitantly by three regularized regression algorithms: LASSO, Elastic Net and Bayesian LASSO.

Terms of use

Please cite the repository and the peer-reviewed publication of the analysis results (DOI: 10.1016/j.jpsychores.2023.111234). The raw data files will be made upon request to the senior study author, Prof. Judith Löffler-Ragg.

Basic usage

The following development packages are required to run the pipeline:

devtools::install_github('PiotrTymoszuk/soucer') ## script sourcing
devtools::install_github('PiotrTymoszuk/ExDA') ## exploratory data analysis and staristical hypothesis testing
devtools::install_github('PiotrTymoszuk/clustTools') ## factor analysis and unsupervised clustering
devtools::install_github('PiotrTymoszuk/caretExtra') ## fit statistics and quality control for the Caret models
devtools::install_github('PiotrTymoszuk/lmqc') ## fit statistics and quality control for linear models
devtools::install_github('PiotrTymoszuk/figur') ## management of figures and tables in Rmd documents
devtools::install_github('PiotrTymoszuk/trafo') ## handling of tabular data

Source 'exec.R' to launch the entire pipeline:

source('exec.R')

Contact

The repository maintainer is Piotr Tymoszuk. Data requests should be addressed to Prof. Judith Löffler-Ragg.

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