OnPrem

The client in the hospital

Premise

OffPrem is a part of a larger project called Premise. This project will bring open and private research into the healthcare industry. Starting with research on COVID-19. Open refers to publically available research processes and results; private refers to mathematically guaranteed privacy for individual patients and hospitals.

OffPrem is a cloud-based deployment that manages the research across healthcare providers. It controls the parameters of experiments being run on distributed workers at individual providers. OnPrem is the on-premise deployment of a worker at an individual provider. So, there is one OffPrem deployment in the cloud, and as many OnPrem deployments as there are participating providers.

Values

1. Privacy - of patients

First, do no harm.

• Only run queries on de-identified data
• Follow principles of differential privacy in your code
• Research must be secure to be private

2. Transparency - of research

Second, share knowledge.

• Do not be transparent if it threatens patient privacy
• Add documentation to your code that explains your intention and expected use

3. Accuracy - of research

Third, find truth.

• Do not go for higher accuracy if it threatens patient privacy or research transparency
• Build your code from state-of-the-art knowledge

Architecture

We designed an architecture with two main components: OnPrem to be hosted on a dedicated hardware box within each hospital, and OffPrem to be hosted on the cloud to manage research.

We use diagrams.net to create up-to-date versions of the system architecture. View it here. Only contributors added to the Medley Health organization are able to edit the document.