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Bioinformatics Sequence Alignment

This is a sequence alignment project for aligning protein sequences and scoring it according to a set of rules. On top of this, it has to run as efficiently as possible with regard to runtime.

It will read in two sequences from text files which are passed in as parameters when running the script, e.g. python sequence_alignment.py file1.txt file2.txt It will print out an optimal alignment of these two sequences, the score and the run time.

Scoring

For matching:

  • +4 A
  • +3 C
  • +2 G
  • +1 T
  • -3 for mismatch
  • -2 for gap

About

Durham University Year 1 assignment to optimise simple sequence alignment scoring in bioinformatics implemented in Python

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