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Perfect alignment of gene island #12

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mweberr opened this issue Jul 5, 2019 · 1 comment
Open

Perfect alignment of gene island #12

mweberr opened this issue Jul 5, 2019 · 1 comment

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@mweberr
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mweberr commented Jul 5, 2019

Hallo , first of all this is a absolutely wonderful visualisation tool for gene maps.
I want to draw gene maps with differing composition of genes due to mutations and frame shifts.
This means that in each line different genes are missing. Still, I want the maps to be aligned according to overlapping genes.

Screenshot from 2019-07-05 14-56-16

Here all lines are aligned to genE, like in the example, but not line 1. Which should aligned to protD. How it would be possible to extend this alignment feature ?

@wilkox
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wilkox commented Jul 12, 2019

I'm afraid there's currently no good way to do this with gggenes and make_alignment_dummies(). Ultimately I think the solution will be to build in some kind of auto-alignment feature that attempts to find the optimal alignment across all the molecules. I've played around with implementing this feature but haven't yet found an algorithm that works in a reasonable amount of time.

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