diff --git a/bio/vep/cache/environment.yaml b/bio/vep/cache/environment.yaml
index 4150aafdd5..7e9b886c0f 100644
--- a/bio/vep/cache/environment.yaml
+++ b/bio/vep/cache/environment.yaml
@@ -3,4 +3,5 @@ channels:
   - bioconda
   - nodefaults
 dependencies:
-  - ensembl-vep =109.3
+  - python >=3.9
+  - ensembl-vep =110.1