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Flexbar — flexible barcode and adapter removal

Flexbar is a software to preprocess high-throughput sequencing data efficiently. It demultiplexes barcoded runs and removes adapter sequences. Moreover, trimming and filtering features are provided. Flexbar increases mapping rates and improves genome and transcriptome assemblies. It supports next-generation sequencing data from Illumina, Roche 454, and the SOLiD platform. Recognition is based on exact overlap sequence alignment.