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TOPUP not compatible with rodent images #118

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eilidhmacnicol opened this issue Nov 11, 2020 · 1 comment
Open

TOPUP not compatible with rodent images #118

eilidhmacnicol opened this issue Nov 11, 2020 · 1 comment
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bug Something isn't working effort: medium Estimated medium effort task impact: high Estimated high impact task nonhumans/rodents pepolar
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@eilidhmacnicol
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eilidhmacnicol commented Nov 11, 2020

Rodent image headers are often scaled ~x10 to get 'human-sized' images
Estimating the field with topup will not work well without this step, so using unscaled images will cause poor estimation of the distortion.

@eugenegkim adjusted FSL's default b02b0.cnf configuration file by dividing the --warpres and --fwhm numbers by 10 to account for this, and ran topup with unscaled images and compared it to the results we get when we scale the headers by 10 and use the original settings (obtained with FSL 5.0.10 running on a Linux server).

scaled images:
image
image
unscaled images:
image
image

These do not demonstrate the worst case, but it was what we had to hand. There is probably some other setting hard-coded (possibly b-spline distance?) that is defined in mm and consequently not optimal for rodent images.

@oesteban oesteban added bug Something isn't working effort: medium Estimated medium effort task impact: high Estimated high impact task nonhumans/rodents pepolar labels Nov 18, 2020
@oesteban oesteban added this to the 1.4.0 milestone Nov 18, 2020
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@oesteban oesteban modified the milestones: 1.4.0, 1.5.0 Nov 26, 2020
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Labels
bug Something isn't working effort: medium Estimated medium effort task impact: high Estimated high impact task nonhumans/rodents pepolar
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