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cuteSV nanopore parameters. #21

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humbleflowers opened this issue Mar 30, 2021 · 1 comment
Open

cuteSV nanopore parameters. #21

humbleflowers opened this issue Mar 30, 2021 · 1 comment

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@humbleflowers
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Any reason why cuteSV report parameters for SV calling are not used?
cuteSV recommends following parameters according to their gitub page.

For ONT data:
--max_cluster_bias_INS 100
--diff_ratio_merging_INS 0.3
--max_cluster_bias_DEL 100
--diff_ratio_merging_DEL 0.3

Thank you.

@biorococo
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Hi @humbleflowers,

The recommended/default parameters have changed in different versions of cuteSV, in internal evaluations we've observed slightly better results by using default parameters, so we stick to them for now. Let me know if you have any other doubt about this.

Thank you very much

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