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Show RO:0004029 associations from Mondo in Phenotype associations section #684

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kevinschaper opened this issue Apr 26, 2024 · 1 comment

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@kevinschaper
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We disease to phenotype associations in Mondo that we're not showing on the site right now, because they're not getting the right category and predicate.

examples:

category subject subject_label predicate object_label object
biolink:Association MONDO:0000986 pleurisy biolink:related_to Pneumonia HP:0002090
biolink:Association MONDO:0000986 pleurisy biolink:related_to Pleuritis HP:0002102
biolink:Association MONDO:0000986 pleurisy biolink:related_to Systemic lupus erythematosus HP:0002725
biolink:Association MONDO:0000986 pleurisy biolink:related_to Pulmonary embolism HP:0002204
biolink:Association MONDO:0000321 typhoidal tularemia biolink:related_to Weight loss HP:0001824
biolink:Association MONDO:0000333 early congenital syphilis biolink:related_to Seizure HP:0001250
biolink:Association MONDO:0000333 early congenital syphilis biolink:related_to Hepatosplenomegaly HP:0001433
biolink:Association MONDO:0000463 Ochoa syndrome biolink:related_to Neurogenic bladder HP:0000011
biolink:Association MONDO:0000490 glomerulosclerosis biolink:related_to Glomerular sclerosis HP:0000096
biolink:Association MONDO:0000875 adult acute monocytic leukemia biolink:related_to Adult onset HP:0003581

Ideally, these should wind up with:

category: biolink:DiseaseToPhenotypicFeatureAssociation
predicate: biolink:has_phenotype

I created a biolink PR that should take care of the predicate (assuming kgx will use the narrow mapping?), but it's important to also make sure we populate the category with biolink:DiseaseToPhenotypicFeatureAssociation - I don't know how practical is to populate categories based on predicate + domain & range? What do you think @caufieldjh

@kevinschaper kevinschaper added this to the 2024-05 Release milestone Apr 26, 2024
@caufieldjh
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Looking into it. To show these in the Monarch interface, is it enough to just have the has_phenotype predicate? I'm guessing it is not

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