Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

random_codon_table not random for Isoleucine #83

Open
amine-abdeljaoued opened this issue May 1, 2024 · 2 comments
Open

random_codon_table not random for Isoleucine #83

amine-abdeljaoued opened this issue May 1, 2024 · 2 comments

Comments

@amine-abdeljaoued
Copy link

The random_codon_table dictionary

"I": {"ATA": 0.07, "ATC": 0.42, "ATT": 0.51},

is biased for Isoleucine (I) with unequal probabilities for the three codons that code for it, while it has equal probabilities for all other Amino Acids.

@ericmjl
Copy link
Contributor

ericmjl commented May 1, 2024

This is a good catch, @amine-abdeljaoued! Let me check with @ndousis -- this definitely feels like a bug, right? Random is defined as "uniform probabilities" for the random_codon_table, just as the others are defined, so it looks like this bug needs to be fixed.

@ndousis
Copy link
Contributor

ndousis commented May 3, 2024

Yeah, that looks like a bug!

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

3 participants