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text definition is "the abnormal accumulation of sphingomyelin in the plasma membrane of cells of the nervous tissue, liver and spleen, usually due to sphingomyelinase deficiency" but eq uses a GO process term so the the reasoner would put this under metabolism not level.
There is also a term for 'abnormal lipolysis' that I moved to be under metabolism and the reasoner infers this to be a parent of sphingomyelinosis.
Question is sphingomyelinosis meant to be the abnormal process or the abnormal accumulation?
The text was updated successfully, but these errors were encountered:
annotations are a mix of increased level and decreased activity
also some annotations indicate accumulation in a subset of the tissues listed not all 3 tissues
Googling this returns primarily links to Niemann Pick disease
description also appears to be more the disease then a general change in either level or process
I'm inclined to obsolete this term and replace with a general increased level term
at least we should remove the eq as it does not match the text definition
text definition is "the abnormal accumulation of sphingomyelin in the plasma membrane of cells of the nervous tissue, liver and spleen, usually due to sphingomyelinase deficiency" but eq uses a GO process term so the the reasoner would put this under metabolism not level.
There is also a term for 'abnormal lipolysis' that I moved to be under metabolism and the reasoner infers this to be a parent of sphingomyelinosis.
Question is sphingomyelinosis meant to be the abnormal process or the abnormal accumulation?
The text was updated successfully, but these errors were encountered: