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allelic copy number for segments #364

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jennyp76 opened this issue Apr 13, 2024 · 0 comments
Open

allelic copy number for segments #364

jennyp76 opened this issue Apr 13, 2024 · 0 comments

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@jennyp76
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jennyp76 commented Apr 13, 2024

Hi, I want to know the allelic copy number for each segment listed in _dnacopy.seg file.
Previous you mentioned that such information is provided by callLOH() (loh.csv) file.
Yet, I found different start and end positions for some segments. I attached the difference below comparing _dnacopy.seg file and loh.csv file. More precisely, the start position and the end position for each chromosome is different.
What I am intending to do is calculate whole-genome duplicated rate. A sample is considered to have undergone WGD if greater than 50% of their autosomal genome had an major-copy nuumber greater than or equal to two.
For this, I need allelic copy number for segment listed in _dnacopy.seg file.
I have already calculated genome alteration rate based on the segments in the _dnacopy.seg.file.

Thank you
<log.csv file>
image

<dnacopy.seg>
image

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